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(PubMed) Rebouche CJ, Lombard KA, Chenard CA

Certain sequences are more susceptible than others, particularly those adjacent to aspartate residues

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Important considerations for ongoing treatment: Regular review with the prescribing healthcare professional is essential Treatment should be discontinued if no clear benefit is observed after an adequate trial period (typically 812 weeks) Do not delay seeking medical attention for new or worsening symptoms Be alert to red flag symptoms requiring urgent assessment, such as unexplained weight loss, persistent fever, chest pain, or suicidal thoughts Patients should maintain realistic expectations , recognising that robust evidence for clinical benefits remains limited